Monday, August 30, 2010

CME : Pneumonia


I like 'picture'.

Restarted : Diclofenac

I need to get ‘myself’ back. I’m quite busy for the last 2 weeks preparing for the ‘event’, hope my friends can attend the wedding ceremony. .

I like drugs. Let’s learn about diclofenac.

According to National Drug List (KKM) and MOH Drug Formulary, diclofenac available in :
• Diclofenac 1% Emulgel
• Diclofenac Sodium 12.5 mg Suppository
• Diclofenac Sodium 25 mg Suppository
• Diclofenac Sodium 50 mg Suppository
• Diclofenac Sodium 50 mg Tablet/Capsule
• Diclofenac Sodium 75 mg/3 ml Injection

According to BP2010, preparation of Diclofenac :
• Prolonged-release Diclofenac Capsules
• Gastro-resistant Diclofenac Tablets
• Prolonged-release Diclofenac Tablets

It’s a simple lesson. 

Wednesday, August 18, 2010

Guestbook

Emailing system is better than sms unless no internet connection available! huhu

Thursday, August 12, 2010

CKD Stage

0) Normal kidney function – GFR above 90mL/min/1.73m2 and no proteinuria

1) CKD1 – GFR above 90mL/min/1.73m2 with evidence of kidney damage
2) CKD2 (Mild) – GFR of 60 to 89 mL/min/1.73m2 with evidence of kidney damage
3) CKD3 (Moderate) – GFR of 30 to 59 mL/min/1.73m2
4) CKD4 (Severe) – GFR of 15 to 29 mL/min/1.73m2
5) CKD5 Kidney failure - GFR less than 15 mL/min/1.73m2 Some people add CKD5D for those stage 5 patients requiring dialysis; many patients in CKD5 are not yet on dialysis.

My group made a wrong classification. Luckily, the preceptor did not aware about that.

Tuesday, August 10, 2010

Seriousness and Severity

The American Food and Drug Administration defines a serious adverse event as one when the patient outcome is one of the following:

* Death
* Life-Threatening
* Hospitalization (initial or prolonged)
* Disability - significant, persistent, or permanent change, impairment, damage or disruption in the patient's body function/structure, physical activities or quality of life.
* Congenital Anomaly
* Requires Intervention to Prevent Permanent Impairment or Damage

Severity is a point on an arbitrary scale of intensity of the adverse event in question. The terms "severe" and "serious" when applied to adverse events are technically very different. They are easily confused but can not be used interchangeably, require care in usage.

A headache is severe, if it causes intense pain. There are scales like "visual analog scale" that help us assess the severity. On the other hand, a headache can hardly ever be serious, unless it also satisfies the criteria for seriousness listed above.

I'm just a little bit confused....